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Protective Effects of Let-7a and Let-7b on Oxidized Low-Density Lipoprotein Induced Endothelial Cell Injuries

Lectin-like low-density lipoprotein receptor 1 (LOX-1) is a receptor for oxidized low density lipoprotein (oxLDL) in endothelial cells. The activation of LOX-1 by oxLDL stimulates the apoptosis and dysfunction of endothelial cells, and contributes to atherogenesis. However, the regulatory factors fo...

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Detalles Bibliográficos
Autores principales: Bao, Mei-hua, Zhang, Yi-wen, Lou, Xiao-ya, Cheng, Yu, Zhou, Hong-hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172475/
https://www.ncbi.nlm.nih.gov/pubmed/25247304
http://dx.doi.org/10.1371/journal.pone.0106540