Activity-Modulating Monoclonal Antibodies to the Human Serine Protease HtrA3 Provide Novel Insights into Regulating HtrA Proteolytic Activities

Mammalian HtrA (high temperature requirement factor A) proteases, comprising 4 multi-domain members HtrA1-4, play important roles in a number of normal cellular processes as well as pathological conditions such as cancer, arthritis, neurodegenerative diseases and pregnancy disorders. However, how Ht...

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Detalles Bibliográficos
Autores principales: Singh, Harmeet, Nero, Tracy L., Wang, Yao, Parker, Michael W., Nie, Guiying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172569/
https://www.ncbi.nlm.nih.gov/pubmed/25248123
http://dx.doi.org/10.1371/journal.pone.0108235

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172569/
https://www.ncbi.nlm.nih.gov/pubmed/25248123
http://dx.doi.org/10.1371/journal.pone.0108235

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