DMH1 Increases Glucose Metabolism through Activating Akt in L6 Rat Skeletal Muscle Cells

DMH1(4-[6-(4-Isopropoxyphenyl)pyrazolo [1,5-a]pyrimidin-3-yl] quinoline) is a compound C analogue with the structural modifications at the 3- and 6-positions in pyrazolo[1,5-a]pyrimidine backbone. Compound C was reported to inhibit both AMPK and Akt. Our preliminary work found that DMH1 activated Ak...

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Detalles Bibliográficos
Autores principales: Xie, Xin, Xu, Xiao-Ming, Li, Na, Zhang, Yong-Hui, Zhao, Yu, Ma, Chun-Yan, Dong, De-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172596/
https://www.ncbi.nlm.nih.gov/pubmed/25247550
http://dx.doi.org/10.1371/journal.pone.0107776

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172596/
https://www.ncbi.nlm.nih.gov/pubmed/25247550
http://dx.doi.org/10.1371/journal.pone.0107776

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