Allopregnanolone and Its Precursor Progesterone Do Not Reduce Injury after Experimental Stroke in Hypertensive Rats – Role of Postoperative Temperature Regulation?

Allopregnanolone is a neurosteroid synthesized from progesterone in brain. It increases inhibition through modulation of the gamma-aminobutyric acid type A (GABA-A) receptor. Both agents are putative neuroprotectants after ischemic stroke. We sought to confirm their effectiveness in a hypertensive r...

Descripción completa

Detalles Bibliográficos
Autores principales: Spratt, Neil J., Tomkins, Amelia J., Pepperall, Debbie, McLeod, Damian D., Calford, Mike B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172598/
https://www.ncbi.nlm.nih.gov/pubmed/25248155
http://dx.doi.org/10.1371/journal.pone.0107752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172598/
https://www.ncbi.nlm.nih.gov/pubmed/25248155
http://dx.doi.org/10.1371/journal.pone.0107752

Ejemplares similares