mTORC2-SGK-1 acts in two environmentally responsive pathways with opposing effects on longevity

The nematode worm Caenorhabditis elegans provides a powerful system for elucidating how genetic, metabolic, nutritional, and environmental factors influence aging. The mechanistic target of rapamycin (mTOR) kinase is important in growth, disease, and aging and is present in the mTORC1 and mTORC2 com...

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Detalles Bibliográficos
Autores principales: Mizunuma, Masaki, Neumann-Haefelin, Elke, Moroz, Natalie, Li, Yujie, Blackwell, T Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172656/
https://www.ncbi.nlm.nih.gov/pubmed/25040785
http://dx.doi.org/10.1111/acel.12248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172656/
https://www.ncbi.nlm.nih.gov/pubmed/25040785
http://dx.doi.org/10.1111/acel.12248

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