Dual Role of Endothelial Nitric Oxide Synthase in Oxidized LDL-Induced, p66(Shc)-Mediated Oxidative Stress in Cultured Human Endothelial Cells

BACKGROUND: The aging gene p66(Shc), is an important mediator of oxidative stress-induced vascular dysfunction and disease. In cultured human aortic endothelial cells (HAEC), p66(Shc) deletion increases endothelial nitric oxide synthase (eNOS) expression and nitric oxide (NO) bioavailability via pro...

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Detalles Bibliográficos
Autores principales: Shi, Yi, Lüscher, Thomas F., Camici, Giovanni G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172699/
https://www.ncbi.nlm.nih.gov/pubmed/25247687
http://dx.doi.org/10.1371/journal.pone.0107787

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172699/
https://www.ncbi.nlm.nih.gov/pubmed/25247687
http://dx.doi.org/10.1371/journal.pone.0107787

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