Dual Role of Endothelial Nitric Oxide Synthase in Oxidized LDL-Induced, p66(Shc)-Mediated Oxidative Stress in Cultured Human Endothelial Cells

BACKGROUND: The aging gene p66(Shc), is an important mediator of oxidative stress-induced vascular dysfunction and disease. In cultured human aortic endothelial cells (HAEC), p66(Shc) deletion increases endothelial nitric oxide synthase (eNOS) expression and nitric oxide (NO) bioavailability via pro...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Yi, Lüscher, Thomas F., Camici, Giovanni G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172699/
https://www.ncbi.nlm.nih.gov/pubmed/25247687
http://dx.doi.org/10.1371/journal.pone.0107787

Ejemplares similares

Ejemplares similares