3-Dimensional Culture Systems for Anti-Cancer Compound Profiling and High-Throughput Screening Reveal Increases in EGFR Inhibitor-Mediated Cytotoxicity Compared to Monolayer Culture Systems

3-dimensional (3D) culture models have the potential to bridge the gap between monolayer cell culture and in vivo studies. To benefit anti-cancer drug discovery from 3D models, new techniques are needed that enable their use in high-throughput (HT) screening amenable formats. We have established min...

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Detalles Bibliográficos
Autores principales: Howes, Amy L., Richardson, Robyn D., Finlay, Darren, Vuori, Kristiina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172726/
https://www.ncbi.nlm.nih.gov/pubmed/25247711
http://dx.doi.org/10.1371/journal.pone.0108283

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172726/
https://www.ncbi.nlm.nih.gov/pubmed/25247711
http://dx.doi.org/10.1371/journal.pone.0108283

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