3′-Deoxy-3′-[(18)F]-Fluorothymidine PET Imaging Reflects PI3K-mTOR-Mediated Pro-Survival Response to Targeted Therapy in Colorectal Cancer

Biomarkers that predict response to targeted therapy in oncology are an essential component of personalized medicine. In preclinical treatment response studies that featured models of wild-type KRAS or mutant BRAF colorectal cancer treated with either cetuximab or vemurafenib, respectively, we illus...

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Detalles Bibliográficos
Autores principales: McKinley, Eliot T., Zhao, Ping, Coffey, Robert J., Washington, M. Kay, Manning, H. Charles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172755/
https://www.ncbi.nlm.nih.gov/pubmed/25247710
http://dx.doi.org/10.1371/journal.pone.0108193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172755/
https://www.ncbi.nlm.nih.gov/pubmed/25247710
http://dx.doi.org/10.1371/journal.pone.0108193

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