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Natural Variability of Kozak Sequences Correlates with Function in a Zebrafish Model

In eukaryotes, targeting the small ribosomal subunit to the mRNA transcript requires a Kozak sequence at the translation initiation site. Despite the critical importance of the Kozak sequence to regulation of gene expression, there have been no correlation studies between its natural variance and ef...

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Detalles Bibliográficos
Autores principales: Grzegorski, Steven J., Chiari, Estelle F., Robbins, Amy, Kish, Phillip E., Kahana, Alon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172775/
https://www.ncbi.nlm.nih.gov/pubmed/25248153
http://dx.doi.org/10.1371/journal.pone.0108475