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Role of cullin-elonginB-elonginC E3 complex in bovine immunodeficiency virus and maedi-visna virus Vif-mediated degradation of host A3Z2-Z3 proteins

BACKGROUND: All lentiviruses except equine infectious anemia virus (EIVA) antagonize antiviral family APOBEC3 (A3) proteins of the host through viral Vif proteins. The mechanism by which Vif of human, simian or feline immunodeficiency viruses (HIV/SIV/FIV) suppresses the corresponding host A3s has b...

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Detalles Bibliográficos
Autores principales: Zhang, Jingyao, Wu, Jiaxin, Wang, Weiran, Wu, Hui, Yu, Bin, Wang, Jiawen, Lv, Mingyu, Wang, Xiaodan, Zhang, Haihong, Kong, Wei, Yu, Xianghui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172784/
https://www.ncbi.nlm.nih.gov/pubmed/25213124
http://dx.doi.org/10.1186/s12977-014-0077-9