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Enhanced monocyte chemoattractant protein-1 production in aging mice exaggerates cardiac depression during endotoxemia

INTRODUCTION: Endotoxemia and the systemic inflammatory response syndrome have a significant impact on post-surgery outcome, particularly in the elderly. The cytokine response to endotoxin is altered by aging. We tested the hypothesis that vulnerability to endotoxemic cardiac depression increases wi...

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Detalles Bibliográficos
Autores principales: Slimani, Hanan, Zhai, Yufeng, Yousif, Nasser G, Ao, Lihua, Zeng, Qingchun, Fullerton, David A, Meng, Xianzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172828/
https://www.ncbi.nlm.nih.gov/pubmed/25209241
http://dx.doi.org/10.1186/s13054-014-0527-8