Atovaquone and quinine anti-malarials inhibit ATP binding cassette transporter activity

BACKGROUND: Therapeutic blood plasma concentrations of anti-malarial drugs are essential for successful treatment. Pharmacokinetics of pharmaceutical compounds are dependent of adsorption, distribution, metabolism, and excretion. ATP binding cassette (ABC) transport proteins are particularly involve...

Descripción completa

Detalles Bibliográficos
Autores principales: Rijpma, Sanna R, van den Heuvel, Jeroen JMW, van der Velden, Maarten, Sauerwein, Robert W, Russel, Frans GM, Koenderink, Jan B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172838/
https://www.ncbi.nlm.nih.gov/pubmed/25218605
http://dx.doi.org/10.1186/1475-2875-13-359

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172838/
https://www.ncbi.nlm.nih.gov/pubmed/25218605
http://dx.doi.org/10.1186/1475-2875-13-359

Ejemplares similares