Inhibition of proliferation and migration of luminal and claudin-low breast cancer cells by PDGFR inhibitors

BACKGROUND: Platelet-derived growth factors (PDGFs) bind to two receptors, PDGFRα and PDGFRβ to mediate cell proliferation, migration and survival. Although epithelial cells typically do not express high levels of PDGFRs, their expression has been reported to increase in breast cancer cells that hav...

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Detalles Bibliográficos
Autores principales: Stalker, Leanne, Pemberton, James, Moorehead, Roger A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172847/
https://www.ncbi.nlm.nih.gov/pubmed/25253994
http://dx.doi.org/10.1186/s12935-014-0089-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172847/
https://www.ncbi.nlm.nih.gov/pubmed/25253994
http://dx.doi.org/10.1186/s12935-014-0089-5

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