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Computational Biophysical, Biochemical, and Evolutionary Signature of Human R-Spondin Family Proteins, the Member of Canonical Wnt/β-Catenin Signaling Pathway

In human, Wnt/β-catenin signaling pathway plays a significant role in cell growth, cell development, and disease pathogenesis. Four human (Rspo)s are known to activate canonical Wnt/β-catenin signaling pathway. Presently, (Rspo)s serve as therapeutic target for several human diseases. Henceforth, ba...

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Detalles Bibliográficos
Autores principales: Sharma, Ashish Ranjan, Chakraborty, Chiranjib, Lee, Sang-Soo, Sharma, Garima, Yoon, Jeong Kyo, George Priya Doss, C., Song, Dong-Keun, Nam, Ju-Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172882/
https://www.ncbi.nlm.nih.gov/pubmed/25276837
http://dx.doi.org/10.1155/2014/974316