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Patched Targeting Peptides for Imaging and Treatment of Hedgehog Positive Breast Tumors

High tumor hedgehog expression is correlated with poor prognosis in invasive ductal carcinoma. Peptides which bind the patched receptor have recently been reported to have a growth inhibitory effect in tumors with activated hedgehog signaling. We sought to examine growth inhibition with these peptid...

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Detalles Bibliográficos
Autores principales: Smith, Daniel, Kong, Fanlin, Yang, David, Larson, Richard, Sims-Mourtada, Jennifer, Woodward, Wendy A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172929/
https://www.ncbi.nlm.nih.gov/pubmed/25276795
http://dx.doi.org/10.1155/2014/525680