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Influence of intrathecal delivery of bone marrow-derived mesenchymal stem cells on spinal inflammation and pain hypersensitivity in a rat model of peripheral nerve injury

BACKGROUND: Multipotent mesenchymal stem (stromal) cells (MSCs) have been credited with immunomodulative properties, supporting beneficial outcomes when transplanted into a variety of disease models involving inflammation. Potential mechanisms include the secretion of paracrine factors and the estab...

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Detalles Bibliográficos
Autores principales: Schäfer, Sabrina, Berger, Julie V, Deumens, Ronald, Goursaud, Stéphanie, Hanisch, Uwe-Karsten, Hermans, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172959/
https://www.ncbi.nlm.nih.gov/pubmed/25212534
http://dx.doi.org/10.1186/s12974-014-0157-8