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Influence of intrathecal delivery of bone marrow-derived mesenchymal stem cells on spinal inflammation and pain hypersensitivity in a rat model of peripheral nerve injury
BACKGROUND: Multipotent mesenchymal stem (stromal) cells (MSCs) have been credited with immunomodulative properties, supporting beneficial outcomes when transplanted into a variety of disease models involving inflammation. Potential mechanisms include the secretion of paracrine factors and the estab...
Autores principales: | Schäfer, Sabrina, Berger, Julie V, Deumens, Ronald, Goursaud, Stéphanie, Hanisch, Uwe-Karsten, Hermans, Emmanuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172959/ https://www.ncbi.nlm.nih.gov/pubmed/25212534 http://dx.doi.org/10.1186/s12974-014-0157-8 |
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