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Spatial control of the GEN1 Holliday junction resolvase ensures genome stability

Holliday junction (HJ) resolvases are necessary for the processing of persistent recombination intermediates before cell division. Their actions, however, need to be restricted to the late stages of the cell cycle to avoid the inappropriate cleavage of replication intermediates. Control of the yeast...

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Detalles Bibliográficos
Autores principales: Chan, Ying Wai, West, Stephen C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4172962/
https://www.ncbi.nlm.nih.gov/pubmed/25209024
http://dx.doi.org/10.1038/ncomms5844