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Development of prediction tools for diarrhea and rash in breast cancer patients receiving lapatinib in combination with capecitabine
Lapatinib and capecitabine (L-CAP) is effective in HER-2 positive patients with metastatic breast cancer (MBC). However, moderate to severe diarrhea and rash (≥ grade 2) are problematic dose limiting toxicities. Since risk may vary over the course of therapy, we developed repeated measures models to...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173070/ https://www.ncbi.nlm.nih.gov/pubmed/25216762 http://dx.doi.org/10.1007/s10549-014-3126-0 |