Cargando…

Development of prediction tools for diarrhea and rash in breast cancer patients receiving lapatinib in combination with capecitabine

Lapatinib and capecitabine (L-CAP) is effective in HER-2 positive patients with metastatic breast cancer (MBC). However, moderate to severe diarrhea and rash (≥ grade 2) are problematic dose limiting toxicities. Since risk may vary over the course of therapy, we developed repeated measures models to...

Descripción completa

Detalles Bibliográficos
Autores principales: Dranitsaris, George, Lacouture, Mario E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173070/
https://www.ncbi.nlm.nih.gov/pubmed/25216762
http://dx.doi.org/10.1007/s10549-014-3126-0