Repression of the soma-specific transcriptome by Polycomb-repressive complex 2 promotes male germ cell development

Polycomb-repressive complex 2 (PRC2) catalyzes the methylation of histone H3 Lys27 (H3K27) and functions as a critical epigenetic regulator of both stem cell pluripotency and somatic differentiation, but its role in male germ cell development is unknown. Using conditional mutagenesis to remove the c...

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Detalles Bibliográficos
Autores principales: Mu, Weipeng, Starmer, Joshua, Fedoriw, Andrew M., Yee, Della, Magnuson, Terry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173155/
https://www.ncbi.nlm.nih.gov/pubmed/25228648
http://dx.doi.org/10.1101/gad.246124.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173155/
https://www.ncbi.nlm.nih.gov/pubmed/25228648
http://dx.doi.org/10.1101/gad.246124.114

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