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A quantitative 14-3-3 interaction screen connects the nuclear exosome targeting complex to the DNA damage response

RNA metabolism is altered following DNA damage, but the underlying mechanisms are not well understood. Through a 14-3-3 interaction screen for DNA damage-induced protein interactions in human cells, we identified protein complexes connected to RNA biology. These include the nuclear exosome targeting...

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Detalles Bibliográficos
Autores principales: Blasius, Melanie, Wagner, Sebastian A., Choudhary, Chunaram, Bartek, Jiri, Jackson, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173157/
https://www.ncbi.nlm.nih.gov/pubmed/25189701
http://dx.doi.org/10.1101/gad.246272.114