Nanocomplexes of an insulinotropic drug: optimization, microparticle formation, and antidiabetic activity in rats

The aim of the present work was to test the ability of two non-diabetogenic carbohydrates to intranasally deliver the insulinotropic drug repaglinide (REP) for controlling blood glucose level. REP was loaded onto chitosan/alginate nanocomplexes (NCs) suitable for mucosal delivery and uptake. Improve...

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Detalles Bibliográficos
Autores principales: Elmowafy, Enas, Osman, Rihab, El-Shamy, Abdel Hameed, Awad, Gehanne AS
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173756/
https://www.ncbi.nlm.nih.gov/pubmed/25258534
http://dx.doi.org/10.2147/IJN.S66876

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173756/
https://www.ncbi.nlm.nih.gov/pubmed/25258534
http://dx.doi.org/10.2147/IJN.S66876

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