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Nanocomplexes of an insulinotropic drug: optimization, microparticle formation, and antidiabetic activity in rats
The aim of the present work was to test the ability of two non-diabetogenic carbohydrates to intranasally deliver the insulinotropic drug repaglinide (REP) for controlling blood glucose level. REP was loaded onto chitosan/alginate nanocomplexes (NCs) suitable for mucosal delivery and uptake. Improve...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove Medical Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173756/ https://www.ncbi.nlm.nih.gov/pubmed/25258534 http://dx.doi.org/10.2147/IJN.S66876 |