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Abundant and Diverse Clustered Regularly Interspaced Short Palindromic Repeat Spacers in Clostridium difficile Strains and Prophages Target Multiple Phage Types within This Pathogen

Clostridium difficile is an important human-pathogenic bacterium causing antibiotic-associated nosocomial infections worldwide. Mobile genetic elements and bacteriophages have helped shape C. difficile genome evolution. In many bacteria, phage infection may be controlled by a form of bacterial immun...

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Detalles Bibliográficos
Autores principales: Hargreaves, Katherine R., Flores, Cesar O., Lawley, Trevor D., Clokie, Martha R. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173771/
https://www.ncbi.nlm.nih.gov/pubmed/25161187
http://dx.doi.org/10.1128/mBio.01045-13