Viral Pathogen-Associated Molecular Patterns Regulate Blood-Brain Barrier Integrity via Competing Innate Cytokine Signals

Pattern recognition receptor (PRR) detection of pathogen-associated molecular patterns (PAMPs), such as viral RNA, drives innate immune responses against West Nile virus (WNV), an emerging neurotropic pathogen. Here we demonstrate that WNV PAMPs orchestrate endothelial responses to WNV via competing...

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Detalles Bibliográficos
Autores principales: Daniels, Brian P., Holman, David W., Cruz-Orengo, Lillian, Jujjavarapu, Harsha, Durrant, Douglas M., Klein, Robyn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173776/
https://www.ncbi.nlm.nih.gov/pubmed/25161189
http://dx.doi.org/10.1128/mBio.01476-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173776/
https://www.ncbi.nlm.nih.gov/pubmed/25161189
http://dx.doi.org/10.1128/mBio.01476-14

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