Cargando…
Viral Pathogen-Associated Molecular Patterns Regulate Blood-Brain Barrier Integrity via Competing Innate Cytokine Signals
Pattern recognition receptor (PRR) detection of pathogen-associated molecular patterns (PAMPs), such as viral RNA, drives innate immune responses against West Nile virus (WNV), an emerging neurotropic pathogen. Here we demonstrate that WNV PAMPs orchestrate endothelial responses to WNV via competing...
Autores principales: | Daniels, Brian P., Holman, David W., Cruz-Orengo, Lillian, Jujjavarapu, Harsha, Durrant, Douglas M., Klein, Robyn S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173776/ https://www.ncbi.nlm.nih.gov/pubmed/25161189 http://dx.doi.org/10.1128/mBio.01476-14 |
Ejemplares similares
-
CCR5 limits cortical viral loads during West Nile virus infection of the central nervous system
por: Durrant, Douglas M., et al.
Publicado: (2015) -
Knocking on Closed Doors: Host Interferons Dynamically Regulate Blood-Brain Barrier Function during Viral Infections of the Central Nervous System
por: Daniels, Brian P., et al.
Publicado: (2015) -
Chemokines Referee Inflammation within the Central Nervous System during Infection and Disease
por: Durrant, Douglas M., et al.
Publicado: (2014) -
Chemokines in the balance: maintenance of homeostasis and protection at CNS barriers
por: Williams, Jessica L., et al.
Publicado: (2014) -
Acute Infection of Viral Pathogens and Their Innate Immune Escape
por: Rai, Kul Raj, et al.
Publicado: (2021)