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Substance P reduces TNF-α-induced apoptosis in human tenocytes through NK-1 receptor stimulation

BACKGROUND: It has been hypothesised that an upregulation of the neuropeptide substance P (SP) and its preferred receptor, the neurokinin-1 receptor (NK-1 R), is a causative factor in inducing tenocyte hypercellularity, a characteristic of tendinosis, through both proliferative and antiapoptotic sti...

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Detalles Bibliográficos
Autores principales: Backman, Ludvig J, Eriksson, Daniella E, Danielson, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4173875/
https://www.ncbi.nlm.nih.gov/pubmed/23996004
http://dx.doi.org/10.1136/bjsports-2013-092438