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Viral and host factors determine innate immune responses in airway epithelial cells from children with wheeze and atopy

BACKGROUND: Airway epithelial cells (AEC) from patients with asthma, appear to have an impaired interferon (IFN)-β and -λ response to infection with rhinovirus. OBJECTIVES: To determine if impaired IFN responses can be identified in young children at risk of developing asthma due to atopy and/or ear...

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Detalles Bibliográficos
Autores principales: Spann, Kirsten M, Baturcam, Engin, Schagen, Johanna, Jones, Carmen, Straub, Claire P, Preston, F Maxine, Chen, Linping, Phipps, Simon, Sly, Peter D, Fantino, Emmanuelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174127/
https://www.ncbi.nlm.nih.gov/pubmed/24811725
http://dx.doi.org/10.1136/thoraxjnl-2013-204908