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Viral and host factors determine innate immune responses in airway epithelial cells from children with wheeze and atopy
BACKGROUND: Airway epithelial cells (AEC) from patients with asthma, appear to have an impaired interferon (IFN)-β and -λ response to infection with rhinovirus. OBJECTIVES: To determine if impaired IFN responses can be identified in young children at risk of developing asthma due to atopy and/or ear...
Autores principales: | Spann, Kirsten M, Baturcam, Engin, Schagen, Johanna, Jones, Carmen, Straub, Claire P, Preston, F Maxine, Chen, Linping, Phipps, Simon, Sly, Peter D, Fantino, Emmanuelle |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174127/ https://www.ncbi.nlm.nih.gov/pubmed/24811725 http://dx.doi.org/10.1136/thoraxjnl-2013-204908 |
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