TP53 and PIK3CA gene mutations in adenocarcinoma, squamous cell carcinoma and high-grade intraepithelial neoplasia of the cervix

BACKGROUND: Mutations in the tumor suppressor gene TP53 and proto-oncogene PIK3CA and alterations of p53 and PIK3CA AKT mTOR pathways are common events in several human cancers. We focused on the analysis of TP53 and PIK3CA gene variations in adenocarcinoma, squamous cell carcinoma as well as in int...

Descripción completa

Detalles Bibliográficos
Autores principales: Tornesello, Maria Lina, Annunziata, Clorinda, Buonaguro, Luigi, Losito, Simona, Greggi, Stefano, Buonaguro, Franco M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174264/
https://www.ncbi.nlm.nih.gov/pubmed/25220666
http://dx.doi.org/10.1186/s12967-014-0255-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174264/
https://www.ncbi.nlm.nih.gov/pubmed/25220666
http://dx.doi.org/10.1186/s12967-014-0255-5

Ejemplares similares