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Secreted production of assembled Norovirus virus-like particles from Pichia pastoris

BACKGROUND: Norovirus virus-like particles (NoV VLPs) have recently been explored as potential vaccine platforms due to their ability to produce an effective immune response. Expression of the main structural protein, VP1, leads to formation of self-assembled particles with similar characteristics t...

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Detalles Bibliográficos
Autores principales: Tomé-Amat, Jaime, Fleischer, Lauren, Parker, Stephanie A, Bardliving, Cameron L, Batt, Carl A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174286/
https://www.ncbi.nlm.nih.gov/pubmed/25201129
http://dx.doi.org/10.1186/s12934-014-0134-z