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Secreted production of assembled Norovirus virus-like particles from Pichia pastoris
BACKGROUND: Norovirus virus-like particles (NoV VLPs) have recently been explored as potential vaccine platforms due to their ability to produce an effective immune response. Expression of the main structural protein, VP1, leads to formation of self-assembled particles with similar characteristics t...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174286/ https://www.ncbi.nlm.nih.gov/pubmed/25201129 http://dx.doi.org/10.1186/s12934-014-0134-z |