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Detecting translational regulation by change point analysis of ribosome profiling data sets

Ribo-Seq maps the location of translating ribosomes on mature mRNA transcripts. While during normal translation, ribosome density is constant along the length of the mRNA coding region, this can be altered in response to translational regulatory events. In the present study, we developed a method to...

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Detalles Bibliográficos
Autores principales: Zupanic, Anze, Meplan, Catherine, Grellscheid, Sushma N., Mathers, John C., Kirkwood, Tom B.L., Hesketh, John E., Shanley, Daryl P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174433/
https://www.ncbi.nlm.nih.gov/pubmed/25147239
http://dx.doi.org/10.1261/rna.045286.114