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In vivo tmRNA protection by SmpB and pre-ribosome binding conformation in solution

TmRNA is an abundant RNA in bacteria with tRNA and mRNA features. It is specialized in trans-translation, a translation rescuing system. We demonstrate that its partner protein SmpB binds the tRNA-like region (TLD) in vivo and chaperones the fold of the TLD-H2 region. We use an original approach com...

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Detalles Bibliográficos
Autores principales: Ranaei-Siadat, Ehsan, Mérigoux, Cécile, Seijo, Bili, Ponchon, Luc, Saliou, Jean-Michel, Bernauer, Julie, Sanglier-Cianférani, Sarah, Dardel, Fréderic, Vachette, Patrice, Nonin-Lecomte, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174442/
https://www.ncbi.nlm.nih.gov/pubmed/25135523
http://dx.doi.org/10.1261/rna.045674.114