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Elevated SRPK1 lessens apoptosis in breast cancer cells through RBM4-regulated splicing events

Imbalanced splicing of premessenger RNA is typical of tumorous malignancies, and the regulatory mechanisms involved in several tumorigenesis-associated splicing events are identified. Elevated expression of serine-arginine protein kinase 1 (SRPK1) may participate in the pathway responsible for the d...

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Detalles Bibliográficos
Autores principales: Lin, Jung-Chun, Lin, Ching-Yu, Tarn, Woan-Yuh, Li, Fang-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174443/
https://www.ncbi.nlm.nih.gov/pubmed/25140042
http://dx.doi.org/10.1261/rna.045583.114