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A cluster of methylations in the domain IV of 25S rRNA is required for ribosome stability

In all three domains of life ribosomal RNAs are extensively modified at functionally important sites of the ribosome. These modifications are believed to fine-tune the ribosome structure for optimal translation. However, the precise mechanistic effect of modifications on ribosome function remains la...

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Detalles Bibliográficos
Autores principales: Gigova, Andriana, Duggimpudi, Sujitha, Pollex, Tim, Schaefer, Matthias, Koš, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174444/
https://www.ncbi.nlm.nih.gov/pubmed/25125595
http://dx.doi.org/10.1261/rna.043398.113