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Preferential Effect of Akt2-Dependent Signaling on the Cellular Viability of Ovarian Cancer Cells in Response to EGF

Objective: Overexpression of the epidermal growth factor receptor (EGFR) is associated with the malignant phenotype in many cancers including ovarian cancer, which leads to increased cell proliferation and survival. In spite of emerging EGFR inhibitors as a potentially useful agent, they are largely...

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Detalles Bibliográficos
Autores principales: Khabele, Dineo, Kabir, Syeda M, Dong, Yuanlin, Lee, Eunsook, Rice, Valerie Montgomery, Son, Deok-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174511/
https://www.ncbi.nlm.nih.gov/pubmed/25258648
http://dx.doi.org/10.7150/jca.9688