Cargando…

Preferential Effect of Akt2-Dependent Signaling on the Cellular Viability of Ovarian Cancer Cells in Response to EGF

Objective: Overexpression of the epidermal growth factor receptor (EGFR) is associated with the malignant phenotype in many cancers including ovarian cancer, which leads to increased cell proliferation and survival. In spite of emerging EGFR inhibitors as a potentially useful agent, they are largely...

Descripción completa

Detalles Bibliográficos
Autores principales:	Khabele, Dineo, Kabir, Syeda M, Dong, Yuanlin, Lee, Eunsook, Rice, Valerie Montgomery, Son, Deok-Soo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174511/ https://www.ncbi.nlm.nih.gov/pubmed/25258648 http://dx.doi.org/10.7150/jca.9688

Ejemplares similares

Aspirin Blocks EGF-stimulated Cell Viability in a COX-1 Dependent Manner in Ovarian Cancer Cells
por: Cho, May, et al.
Publicado: (2013)

Characteristics of chemokine signatures elicited by EGF and TNF in ovarian cancer cells
por: Son, Deok-Soo, et al.
Publicado: (2013)

The Therapeutic Potential of Class I Selective Histone Deacetylase Inhibitors in Ovarian Cancer
por: Khabele, Dineo
Publicado: (2014)

Augmented Serum Amyloid A1/2 Mediated by TNF-induced NF-κB in Human Serous Ovarian Epithelial Tumors
por: Choi, Hyeongjwa, et al.
Publicado: (2017)

Bipolar Tumor-Associated Macrophages in Ovarian Cancer as Targets for Therapy
por: Gupta, Vijayalaxmi, et al.
Publicado: (2018)

Heated Intraperitoneal Chemotherapy in the Management of Advanced Ovarian Cancer
por: Jewell, Andrea, et al.
Publicado: (2018)

CXCR2-Driven Ovarian Cancer Progression Involves Upregulation of Proinflammatory Chemokines by Potentiating NF-κB Activation via EGFR-Transactivated Akt Signaling
por: Dong, Yuan-Lin, et al.
Publicado: (2013)

Thailandepsins are new small molecule class I HDAC inhibitors with potent cytotoxic activity in ovarian cancer cells: a preclinical study of epigenetic ovarian cancer therapy
por: Wilson, Andrew J, et al.
Publicado: (2012)

Adrenal Gland Metastasis Is an Unusual Manifestation of Endometrial Cancer
por: Zaidi, Syeda Sadia, et al.
Publicado: (2013)

Inhibitory Effect of Tumor Suppressor p53 on Proinflammatory Chemokine Expression in Ovarian Cancer Cells by Reducing Proteasomal Degradation of IκB
por: Son, Deok-Soo, et al.
Publicado: (2012)

Microenvironmental effects limit efficacy of thymoquinone treatment in a mouse model of ovarian cancer
por: Wilson, Andrew J., et al.
Publicado: (2015)

Thymoquinone enhances cisplatin-response through direct tumor effects in a syngeneic mouse model of ovarian cancer
por: Wilson, Andrew J., et al.
Publicado: (2015)

CXCR2 is a negative regulator of p21 in p53-dependent and independent manner via Akt-mediated Mdm2 in ovarian cancer
por: Ignacio, Rosa Mistica C., et al.
Publicado: (2018)

A Case of Extrauterine Endometrial Stromal Sarcoma in the Colon Diagnosed Three Decades after Hysterectomy for Benign Disease
por: Ayuso, Andres, et al.
Publicado: (2013)

Panobinostat enhances olaparib efficacy by modifying expression of homologous recombination repair and immune transcripts in ovarian cancer
por: Wilson, Andrew J., et al.
Publicado: (2021)

Pharmacological ascorbate induces ‘BRCAness’ and enhances the effects of Poly(ADP-Ribose) polymerase inhibitors against BRCA1/2 wild-type ovarian cancer
por: Ma, Yan, et al.
Publicado: (2020)

NF-κB-Mediated CCL20 Reigns Dominantly in CXCR2-Driven Ovarian Cancer Progression
por: Ignacio, Rosa Mistica C., et al.
Publicado: (2016)

Disparities in ovarian cancer survival at the only NCI-designated cancer center in Kansas
por: Petersen, Shariska, et al.
Publicado: (2020)

Aberrant over-expression of COX-1 intersects multiple pro-tumorigenic pathways in high-grade serous ovarian cancer
por: Wilson, Andrew J., et al.
Publicado: (2015)

Blood type, ABO genetic variants, and ovarian cancer survival
por: Cozzi, Gabriella D., et al.
Publicado: (2017)

Chemokine network during adipogenesis in 3T3-L1 cells: Differential response between growth and proinflammatory factor in preadipocytes vs. adipocytes
por: Kabir, Syeda M, et al.
Publicado: (2014)

Tracking NF-κB activity in tumor cells during ovarian cancer progression in a syngeneic mouse model
por: Wilson, Andrew J, et al.
Publicado: (2013)

Thresholds and timing of pre-operative thrombocytosis and ovarian cancer survival: analysis of laboratory measures from electronic medical records
por: Cozzi, Gabriella D., et al.
Publicado: (2016)

Targeting the EGF Receptor for Ovarian Cancer Therapy
por: Zeineldin, Reema, et al.
Publicado: (2010)

CCNE1 and BRD4 co-amplification in high-grade serous ovarian cancer is associated with poor clinical outcomes
por: Petersen, Shariska, et al.
Publicado: (2020)

Similar requirement for clathrin in EGF- and HGF- stimulated Akt phosphorylation
por: Lucarelli, Stefanie, et al.
Publicado: (2016)

Human papillomavirus vaccination completion rates among gynecological providers: an institutional retrospective review
por: Elsamadicy, Emad A., et al.
Publicado: (2019)

Differential cyclooxygenase expression levels and survival associations in type I and type II ovarian tumors
por: Beeghly-Fadiel, Alicia, et al.
Publicado: (2018)

Clotrimazole Preferentially Inhibits Human Breast Cancer Cell Proliferation, Viability and Glycolysis
por: Furtado, Cristiane M., et al.
Publicado: (2012)

Bypassing cellular EGF receptor dependence through epithelial-to-mesenchymal-like transitions
por: Barr, Sharon, et al.
Publicado: (2008)

Ascites-induced compression alters the peritoneal microenvironment and promotes metastatic success in ovarian cancer
por: Asem, Marwa, et al.
Publicado: (2020)

Cinnamaldehyde Suppressed EGF-Induced EMT Process and Inhibits Ovarian Cancer Progression Through PI3K/AKT Pathway
por: Wang, Yue, et al.
Publicado: (2022)

Expression of p52, a non-canonical NF-kappaB transcription factor, is associated with poor ovarian cancer prognosis
por: Hufnagel, Demetra H., et al.
Publicado: (2020)

Inhibition of the AKT pathway in cholangiocarcinoma by MK2206 reduces cellular viability via induction of apoptosis
por: Wilson, Jacob M, et al.
Publicado: (2015)

Overexpressed cold inducible RNA-binding protein improves cell viability and EGF expression in glial cells
por: Liu, Aijun, et al.
Publicado: (2022)

Incidental placenta increta at the time of prophylactic hysterectomy for Lynch syndrome: Insights into individualized decision-making and surgical timing
por: Nielsen, Tara A., et al.
Publicado: (2015)

Absence of constitutive EGF receptor activation in ovarian cancer cell lines.
por: Ottensmeier, C., et al.
Publicado: (1996)

Early Detection of Treatment-Induced Mitotic Arrest Using Temporal Diffusion Magnetic Resonance Spectroscopy()()
por: Jiang, Xiaoyu, et al.
Publicado: (2016)

Reduction in milk fat globule-EGF factor 8 inhibits triple-negative breast cancer cell viability and migration
por: Yang, Yong, et al.
Publicado: (2019)

LRRK2 kinase plays a critical role in manganese-induced inflammation and apoptosis in microglia
por: Kim, Judong, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_bf5fg34osc7pjb2n387iogm7i5