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Dephosphorylated-uncarboxylated Matrix Gla protein concentration is predictive of vitamin K status and is correlated with vascular calcification in a cohort of hemodialysis patients

BACKGROUND: Matrix Gla protein (MGP) is known to act as a potent local inhibitor of vascular calcifications. However, in order to be active, MGP must be phosphorylated and carboxylated, with this last process being dependent on vitamin K. The present study focused on the inactive form of MGP (dephos...

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Detalles Bibliográficos
Autores principales: Delanaye, Pierre, Krzesinski, Jean-Marie, Warling, Xavier, Moonen, Martial, Smelten, Nicole, Médart, Laurent, Pottel, Hans, Cavalier, Etienne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174604/
https://www.ncbi.nlm.nih.gov/pubmed/25190488
http://dx.doi.org/10.1186/1471-2369-15-145