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Increasing the Efficiency of Parkinson's Disease Treatment Using a poly(lactic-co-glycolic acid) (PLGA) Based L-DOPA Delivery System

To compare the efficacy of L-DOPA administered intranasally in the form of nanoparticles (nano-DOPA) and in standard drug forms using a rat Parkinson's Disease (PD) model. L-DOPA-containing nanoparticles (250±50 nm) were synthesized using the double emulsion method. The efficacy of nano-DOPA th...

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Detalles Bibliográficos
Autores principales: Gambaryan, P.Y., Kondrasheva, I.G., Severin, E.S., Guseva, A.A., Kamensky, A.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174616/
https://www.ncbi.nlm.nih.gov/pubmed/25258572
http://dx.doi.org/10.5607/en.2014.23.3.246