Validating Antibodies to the Cannabinoid CB2 Receptor: Antibody Sensitivity Is Not Evidence of Antibody Specificity

Antibody-based methods for the detection and quantification of membrane integral proteins, in particular, the G protein-coupled receptors (GPCRs), have been plagued with issues of primary antibody specificity. In this report, we investigate one of the most commonly utilized commercial antibodies for...

Descripción completa

Detalles Bibliográficos
Autores principales: Marchalant, Yannick, Brownjohn, Philip W., Bonnet, Amandine, Kleffmann, Torsten, Ashton, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2014
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174627/
https://www.ncbi.nlm.nih.gov/pubmed/24670796
http://dx.doi.org/10.1369/0022155414530995

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174627/
https://www.ncbi.nlm.nih.gov/pubmed/24670796
http://dx.doi.org/10.1369/0022155414530995

Ejemplares similares