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Validating Antibodies to the Cannabinoid CB2 Receptor: Antibody Sensitivity Is Not Evidence of Antibody Specificity
Antibody-based methods for the detection and quantification of membrane integral proteins, in particular, the G protein-coupled receptors (GPCRs), have been plagued with issues of primary antibody specificity. In this report, we investigate one of the most commonly utilized commercial antibodies for...
Autores principales: | Marchalant, Yannick, Brownjohn, Philip W., Bonnet, Amandine, Kleffmann, Torsten, Ashton, John C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174627/ https://www.ncbi.nlm.nih.gov/pubmed/24670796 http://dx.doi.org/10.1369/0022155414530995 |
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