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MICA/B expression is inhibited by unfolded protein response and associated with poor prognosis in human hepatocellular carcinoma

BACKGROUND: MICA/B are major ligands for NK cell activating receptor NKG2D and previous studies showed that the serum level of soluble MICA (sMICA) is an independent prognostic factor for advanced human hepatocellular carcinoma. However, the correlation between cellular MICA/B expression pattern and...

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Detalles Bibliográficos
Autores principales: Fang, Liang, Gong, Jiuyu, Wang, Ying, Liu, Rongrong, Li, Zengshan, Wang, Zhe, Zhang, Yun, Zhang, Chunmei, Song, Chaojun, Yang, Angang, Ting, Jenny P -Y, Jin, Boquan, Chen, Lihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174668/
https://www.ncbi.nlm.nih.gov/pubmed/25228093
http://dx.doi.org/10.1186/s13046-014-0076-7