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LPA-primed astrocytes induce axonal outgrowth of cortical progenitors by activating PKA signaling pathways and modulating extracellular matrix proteins

Lysophosphatidic acid (LPA) is one of the main membrane-derived lysophospholipids, inducing diverse cellular responses like cell proliferation, cell death inhibition, and cytoskeletal rearrangement, and thus is important in many biological processes. In the central nervous system (CNS), post-mitotic...

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Detalles Bibliográficos
Autores principales: Spohr, Tania Cristina Leite de Sampaio e, Dezonne, Rômulo Sperduto, Rehen, Stevens Kastrup, Gomes, Flávia Carvalho Alcantara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174751/
https://www.ncbi.nlm.nih.gov/pubmed/25309328
http://dx.doi.org/10.3389/fncel.2014.00296