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Cardiac hypertrophy in mice expressing unphosphorylatable phospholemman

AIMS: Elevation of intracellular Na in the failing myocardium contributes to contractile dysfunction, the negative force–frequency relationship, and arrhythmias. Although phospholemman (PLM) is recognized to form the link between signalling pathways and Na/K pump activity, the possibility that defec...

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Detalles Bibliográficos
Autores principales: Boguslavskyi, Andrii, Pavlovic, Davor, Aughton, Karen, Clark, James E., Howie, Jacqueline, Fuller, William, Shattock, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174889/
https://www.ncbi.nlm.nih.gov/pubmed/25103111
http://dx.doi.org/10.1093/cvr/cvu182