Effect of Cytosolic pH on Inward Currents Reveals Structural Characteristics of the Proton Transport Cycle in the Influenza A Protein M2 in Cell-Free Membrane Patches of Xenopus oocytes

Transport activity through the mutant D44A of the M2 proton channel from influenza virus A was measured in excised inside-out macro-patches of Xenopus laevis oocytes at cytosolic pH values of 5.5, 7.5 and 8.2. The current-voltage relationships reveal some peculiarities: 1. “Transinhibition”, i.e., i...

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Detalles Bibliográficos
Autores principales: DiFrancesco, Mattia L., Hansen, Ulf-Peter, Thiel, Gerhard, Moroni, Anna, Schroeder, Indra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174909/
https://www.ncbi.nlm.nih.gov/pubmed/25211283
http://dx.doi.org/10.1371/journal.pone.0107406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174909/
https://www.ncbi.nlm.nih.gov/pubmed/25211283
http://dx.doi.org/10.1371/journal.pone.0107406

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