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Effect of Cytosolic pH on Inward Currents Reveals Structural Characteristics of the Proton Transport Cycle in the Influenza A Protein M2 in Cell-Free Membrane Patches of Xenopus oocytes
Transport activity through the mutant D44A of the M2 proton channel from influenza virus A was measured in excised inside-out macro-patches of Xenopus laevis oocytes at cytosolic pH values of 5.5, 7.5 and 8.2. The current-voltage relationships reveal some peculiarities: 1. “Transinhibition”, i.e., i...
Autores principales: | DiFrancesco, Mattia L., Hansen, Ulf-Peter, Thiel, Gerhard, Moroni, Anna, Schroeder, Indra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174909/ https://www.ncbi.nlm.nih.gov/pubmed/25211283 http://dx.doi.org/10.1371/journal.pone.0107406 |
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