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A Defined Zebrafish Line for High-Throughput Genetics and Genomics: NHGRI-1

Substantial intrastrain variation at the nucleotide level complicates molecular and genetic studies in zebrafish, such as the use of CRISPRs or morpholinos to inactivate genes. In the absence of robust inbred zebrafish lines, we generated NHGRI-1, a healthy and fecund strain derived from founder par...

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Detalles Bibliográficos
Autores principales: LaFave, Matthew C., Varshney, Gaurav K., Vemulapalli, Meghana, Mullikin, James C., Burgess, Shawn M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174928/
https://www.ncbi.nlm.nih.gov/pubmed/25009150
http://dx.doi.org/10.1534/genetics.114.166769