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A Defined Zebrafish Line for High-Throughput Genetics and Genomics: NHGRI-1
Substantial intrastrain variation at the nucleotide level complicates molecular and genetic studies in zebrafish, such as the use of CRISPRs or morpholinos to inactivate genes. In the absence of robust inbred zebrafish lines, we generated NHGRI-1, a healthy and fecund strain derived from founder par...
Autores principales: | LaFave, Matthew C., Varshney, Gaurav K., Vemulapalli, Meghana, Mullikin, James C., Burgess, Shawn M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174928/ https://www.ncbi.nlm.nih.gov/pubmed/25009150 http://dx.doi.org/10.1534/genetics.114.166769 |
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