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RNA-Seq Alignment to Individualized Genomes Improves Transcript Abundance Estimates in Multiparent Populations

Massively parallel RNA sequencing (RNA-seq) has yielded a wealth of new insights into transcriptional regulation. A first step in the analysis of RNA-seq data is the alignment of short sequence reads to a common reference genome or transcriptome. Genetic variants that distinguish individual genomes...

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Detalles Bibliográficos
Autores principales: Munger, Steven C., Raghupathy, Narayanan, Choi, Kwangbom, Simons, Allen K., Gatti, Daniel M., Hinerfeld, Douglas A., Svenson, Karen L., Keller, Mark P., Attie, Alan D., Hibbs, Matthew A., Graber, Joel H., Chesler, Elissa J., Churchill, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174954/
https://www.ncbi.nlm.nih.gov/pubmed/25236449
http://dx.doi.org/10.1534/genetics.114.165886